General Cell Lines and Cell Cultures
ATCC Human herpesvirus 5; HCMV Strain AD-169; Quantitative DNA
Quantitative genomic DNA from Human herpesvirus 5 strain AD-169 can be used for assay development, verification, and validation as well as monitoring of day-to-day test variation and lot-to-lot performance of molecular-based assays. The quantitative format allows for the generation of a standard curve for quantitative PCR (qPCR) to determine viral load and for other molecular biology applications.
Eurofins Discoverx PathHunter LTB4R Total Internalization U2OS Cell Line, 2 vials. (93-0810C3)
The PathHunter LTB4R Total Internalization cell line is a stable, engineered cell line for use in studying drug candidates (small molecules or biologics) affecting GPCR activation and internalization. This cell line uses EFC technology to measure ligand-induced internalization of LTB4R via detection of localization to the early endosome. The included cell line overexpresses ProLink-tagged LTB4R and an EA-tagged early endosome protein. Upon ligand-induced receptor activation, resulting internalization of the LTB4R receptor to the early endosome leads to production of EFC signal. This stable modified cell line is provided as two vials of cryopreserved cells. For detailed product information, User Manual and datasheet, visit www.discoverx.com/gpcr.
Enterprise Technology Solutions APC Smart-UPS X, Line Interactive, 2000VA, Rack/tower
APC Smart-UPS X, Line Interactive, 2000VA, Rack/tower
Eurofins Discoverx PathHunter CHO-K1 P2RY11 β-Arrestin Cell Line, 2 vials. (93-0281C2)
The PathHunter P2RY11 cell line is a stable, engineered cell line for use in studying drug candidates (small molecules or biologics) targeting GPCRs. This cell line enables assessment of ligand (e.g. ATP) based activation of P2RY11 GPCR activity via detection of β-arrestin recruitment. The included cell line overexpresses ProLink-tagged P2RY11 and EA-tagged β-Arrestin-2. Activation of P2RY11 stimulates the recruitment of β-Arrestin-2 and produces EFC signal. This stable modified cell line is provided as two vials of cryopreserved cells. For detailed product information, User Manual and datasheet, visit www.discoverx.com/gpcr.
Eurofins Discoverx ChemiScreen NMU1 Neuromedin U Receptor Stable Cell Line, 2 vials. (HTS062C)
The ChemiScreen nMU1 Neuromedin U Receptor Stable Cell Line is an engineered cell line for use in studying drug candidates (small molecules or biologics) targeting GPCRs. This cell line enables assessment of ligand (e.g. Neuromedin U) based activation of nMU1R GPCR activity via detection of increasing levels of intracellular calcium. The included cell line overexpresses nMU1R alongside endogenous high levels of the promiscuous G protein, Gα15, coupling the receptor to the calcium signaling pathway. Upon activation of nMU1R, the resulting calcium activity can be fluorescently assayed. This stable modified cell line is provided as two vials of cryopreserved cells. For detailed product information, visit www.discoverx.com/targets/gpcr-target-biology.
Eurofins Discoverx CHO-K1 FFAR2 (GPR43) Gq Cell Line, 2 vials. (95-1002C2)
The FFAR2 (GPR43) Gq cell line is a stable, engineered cell line for use in studying drug candidates (small molecules or biologics) targeting GPCRs. This cell line enables assessment of ligand (e.g. FFAs) based activation of FFAR2 GPCR activity via detection of increasing levels of intracellular calcium. The included cell line overexpresses FFAR2, a naturally Gq coupled GPCR. Upon activation of FFAR2, the resulting calcium activity can be fluorescently assayed using the Calcium No WashPLUS Detection Kit. This stable modified cell line is provided as two vials of cryopreserved cells. For detailed product information, User Manual and datasheet, visit www.discoverx.com/gpcr.
Electron Microscopy Sciences Specimen Forceps, 114 mm
Stainless steel forceps with serrated tips.
OAL: 114 mm
Eurofins Discoverx RBL-2H3 MRGPRX1 Gq Cell Line, 2 vials. (95-1019C11)
The MRGPRX1 Gq cell line is a stable, engineered cell line for use in studying drug candidates (small molecules or biologics) targeting GPCRs. This cell line enables assessment of ligand (e.g. BAM (8-22)) based activation of MRGPRX1 GPCR activity via detection of increasing levels of intracellular calcium. The included cell line overexpresses MRGPRX1, a naturally Gq coupled GPCR. Upon activation of MRGPRX1, the resulting calcium activity can be fluorescently assayed using the Calcium No WashPLUS Detection Kit. This stable modified cell line is provided as two vials of cryopreserved cells. For detailed product information, User Manual and datasheet, visit www.discoverx.com/gpcr.
Eurofins Discoverx KILR A549 Cell Pool, 2 vials. (97-1005P015)
The KILR A549 cell pool is a stable, engineered target cell pool, which closely reflects the heterogeneous native protein expression of tumor environments, used to measure direct cell death mediated by immunooncology treatments (e.g. checkpoint modulators, bispecifics, CAR-T, etc.) via Antibody Dependent Cell-mediated Cytotoxicity (ADCC), Complement Dependent Cytotoxicity (CDC), and Antibody Dependent Cell Phagocytosis (ADCP). This product uses EFC technology. The cell pool is a heterogeneous population of A549 cells that overexpress a ProLabel-tagged housekeeping gene. Upon effector cells-mediated cell lysis, ProLabel is released to the media, where EA in the detection kit produces an EFC signal proportional to the level of ProLabel released. This allows for calculation of percent lysis of the KILR cell pool. This stable cell pool is provided as two vials of cryopreserved cells. For detailed product information, User Manual and datasheet, visit www.discoverx.com/kilr.
Biochain Institute Inc FDA Standard Frozen Tissue Array - Human Adult Normal, 4 slides/PK
This FDA Standard Frozen Tissue Array is designed according to published Guidance for Submission of Immunohistochemistry Applications to the FDA. Each FDA Standard Frozen Tissue Array package has either two or four slides which contain 30 different human normal tissue types and 3 donors per tissue type. This product is intended for Research Use Only.
Eurofins Discoverx cAMP Hunter CHO-K1 TAAR1 Gs Cell Line, 2 vials. (95-0173C2)
The cAMP Hunter TAAR1 Gs cell line is a stable, engineered cell line for use in studying drug candidates (small molecules or biologics) targeting GPCRs. This cell line enables assessment of ligand (e.g. p-tyramine) based activation of TAAR1 GPCR activity via detection of increasing levels of intracellular cAMP. This product uses EFC technology. The cells overexpress wild type TAAR1, a naturally Gs coupled GPCR. Upon activation of TAAR1, the increase in levels of intracellular cAMP leads to an increased signal from EFC when the cAMP detection kit is applied. This stable modified cell line is provided as two vials of cryopreserved cells. For detailed product information, User Manual and datasheet, visit www.discoverx.com/gpcr.
ATCC HCC 1428; Breast Adenocarcinoma; Human (Homo sapiens)
HCC1428 is an epithelial cell that was isolated from the mammary gland of a 49-year old, White female patient with adenocarcinoma, TNM stage IV, grade 4. The cell was deposited by AF Gazdar and AK Virmani and can be used in cancer research.
ATCC Human herpesvirus 1 DNA; HSV-1 strain KOS
Viral nucleic acids, including virus genomic DNA, in total DNA isolated from Vero cells (ATCC CCL-81) infected with Human herpesvirus 1 (HSV-1) strain KOS (ATCC VR-1493). Virus and host cells are also available through the ATCC Catalog. This product was prepared using methods known to inactivate viruses. It can be used in PCR and other molecular biology applications.
STEMCELL Technologies Human Bone Marrow CD36+ Cells, Frozen, Size: 1 x 10^6 cells
Primary human CD36+ cells were derived from positively selected bone marrow (BM) CD34+ cells. CD34+ cells were cultured in StemSpan™ SFEM II with SCF, EPO, IL-3 and hydrocortisone for 10 days to generate CD36+ cells. BM was collected using heparin as an anticoagulant. CD36 is expressed on erythroid progenitor and lineage cells.Cells were obtained using Institutional Review Board (IRB) approved consent forms and protocols.Certain products are only available in select territories. Please contact your local Sales representative or Product & Scientific Support at techsupport@stemcell.com for further information.Browse our Frequently Asked Questions (FAQs) (https://www.stemcell.com/primary-cells-faq) on Primary Cells.