General Cell Lines and Cell Cultures
Eurofins Discoverx PathHunter U2OS TYRO3 Functional Assay, 2 vials. (93-1110C3)
The PathHunter U2OS TYRO3 Functional Assay provides an easy-to-use cell based assay to study drug candidates (small molecules or biologics) targeting RTKs. This kit assesses RTK activation via detection of activated TYRO3 dimerization-induced SH2 domain protein recruitment. This product uses EFC technology. The included cell line overexpresses ProLink-tagged TYRO3 and an EA-tagged SH2 domain protein. Upon ligand-induced receptor activation, SH2-EA recruitment leads to production of EFC signal. This stable modified cell line is provided as two vials of cryopreserved cells. For detailed product information, User Manual and datasheet, visit www.discoverx.com/kinases.
Eurofins Discoverx ChemiScreen NK1 Tackykinin Receptor Stable Cell Line, 2 vials. (HTS080C)
The ChemiScreen NK1 Tachykinin Receptor Stable Cell Line is an engineered cell line for use in studying drug candidates (small molecules or biologics) targeting GPCRs. This cell line enables assessment of ligand (e.g. tachykinins) based activation of TACR1 GPCR activity via detection of increasing levels of intracellular calcium. The included cell line overexpresses TACR1 alongside endogenous high levels of the promiscuous G protein, Gα15, coupling the receptor to the calcium signaling pathway. Upon activation of TACR1, the resulting calcium activity can be fluorescently assayed. This stable modified cell line is provided as two vials of cryopreserved cells. For detailed product information, visit www.discoverx.com/targets/gpcr-target-biology.
ATCC Rhodospirillum rubrum
Rhodospirillum rubrum strain NCIB 8255 is a whole-genome sequenced type strain. This phototroph is tolerant to oxygen, so strictly anoxic conditions are not required when the vial is thawed.
ATCC Candida albicans; genomic DNA
Genomic DNA isolated from Candida albicans strain SC5314 (ATCC MYA-2876). This product can be used in PCR or other molecular biology applications.
iQ Biosciences Purified Human CD4 T Cells, 10M cells/vial
High-quality, high-viability (> 90%) human CD4 T cells purified from PBMCs of healthy blood donors sourced from a world-renowned blood center. Highly enriched (typically > 90%) post-selection purity achieved via magnetic isolation. All orders come with an iQ Certificate of Analysis.
Amsbio LLC eLuCidate™ HEK 293, TLR2/NF-kB Reporter Cell Line
eLuCidate™ HEK 293 TLR2/NF-kB Reporter Cell Line
Lonza Walkersville Rat Embryonic Dorsal Root Ganglion (eDRG) Neurons
Ready to use Rat Embryonic Dorsal Root Ganglion (DRG) Neurons are suspensions of high quality sensory neurons prepared by standardized methods, and are ready for immediate culture.Benefits:Ready-To-Use No tissue dissection or animal handling required Increased data reproducibilityCharacteristic morphology and staining tests confirm tissue origin and cell typeNegative for mycoplasma, bacteria, yeast and fungiCertificate of Analysis (CoA) is available for every batch Applications:NeurogenesisNeurotransmitter FunctionGene ExpressionSignaling PathwaysElectrophysiologyNeurotoxicityDrug/Compound ScreeningAdvanced Cell Culture ModelsContent:≥ 1,000,000 cryopreserved cells per ampule
Lonza Walkersville hMSC Adipogenic Induction Kit
hMSC Adipogenic Induction SingleQuots Kit is a component of the hMSC Adipogenic Differentiation BulletKitTM and is available separately Stem cells possess the unique ability to differentiate into multiple lineages of cells including adipocytes Lonza s hMSC Adipogenic Differentiation BulletKitTM Medium is a serum containing media system designed to induce adipogenic differentiation of human bone marrow derived mesenchymal stem cells into mature functionally active adipocytes in as few as 19 days Differentiation can then be validated by a variety of methods including the use of Lonza s AdipoRedTM Adipogenic Assay Reagent which provides a quantitative value related to the amount of adipogenic differentiation
ATCC Enterococcus faecalis; OG1RF
Enterococcus faecalis strain OG1RF is a whole-genome sequenced strain used in molecular biology applications. This product is a microbiome standard component.
Eurofins Discoverx PrecisION hNav1.5 Recombinant Stable Cell Line, 2 vials. (CYL3004)
The PrecisION hNav1.5 Recombinant Stable Cell Line is a stable, engineered cell line for use in studying Nav1.5 ion channels, including drug candidates which affect channel function. This cell line enables assessment of ion channel function via detection of electrophysiological signals. The included cell line overexpresses Nav1.5 ion channels. Upon ligand/agonist induced channel activation, response can be detected via automated or manual electrophysiological techniques. This stable modified cell line is provided as two vials of cryopreserved cells. For detailed product information, User Manual and datasheet, visit www.discoverx.com/ion-channels.
Eurofins Discoverx Ready-to-Assay ETA Endothelin Receptor Frozen Cells, 2 Vials of Cells. (HTS070RTA)
The Ready-to-Assay ETA Endothelin Receptor Frozen Cells are a simple, thaw-and-assay cell format for use in studying drug candidates (small molecules or biologics) targeting GPCRs. This assay assesses ligand (e.g. endothelin) based activation of EDNRA GPCR activity via detection of increasing levels of intracellular calcium. The included cell line overexpresses EDNRA alongside endogenous high levels of a promiscuous G-protein, coupling the receptor to the calcium signaling pathway. Upon activation of EDNRA, the resulting calcium activity can be fluorescently assayed. Ready-to-assay kits consist of two vials of the stably modified clonal cell line in a convenient thaw-and-use format. For detailed product information, User manual and datasheet, visit www.discoverx.com/products-applications/frozen-cells.
ATCC Rhizobium radiobacter; genomic DNA
Genomic DNA isolated from Rhizobium radiobacter strain C58. This bacterial strain is also available as ATCC Catalog No. 33970™.
ATCC Staphylococcus simulans
Staphylococcus simulans strain MK 148 is a bacterial type strain that was isolated from human skin. This strain is propagated aerobically.
Biochain Institute Inc Frozen Tissue Section - Human Adult Normal: Prostate, 5 slides/PK
BioChain's tissue products are based on the sample repository network established following the IRB-approved ethical standard and procedures. BioChain's Frozen Tissue Slides are ideal for rapidly identifying cellular localization of RNA or protein. A single human adult normal tissue with 5-10 um thickness is mounted on a positively charged glass slide. The slides are fixed and dehydrated with acetone for consistent results with in situ hybridization and immunohistochemistry. More organs may be available upon request.
Biochain Institute Inc Paraffin Tissue Section - Human Prostate Tumor: Adenocarcinoma, 5 sides/PK
BioChain's tissue products are based on the sample repository network established following the IRB-approved ethical standard and procedures. BioChain's formalin fixed paraffin embedded (FFPE) tissue section line encompasses a large selection of tissue sections which are suitable for immunohistochemistry and in situ hybridization assays. The tissue sections are approximately 5 um thick. Each slide contains tissue from a single human tumor. Documentation of tissues' clinical histories may be available upon request. For those customers who want to perform FFPE DNA and RNA isolation, BioChain can provide tissue section slices in tubes instead of mounting them on glass slides.